Sigmaaldrich material safety data sheet product name. Description of first aid measures general information get medical adviceattention if you feel unwell. Sigmaaldrich offers a number of dl phenylalanine products. Interestingly, several psychotropic drugs mescaline, morphine, codeine, and papaverine also have. This essential amino acid is classified as neutral, and nonpolar because of the inert and hydrophobic nature of the benzyl side chain. An essential amino acid, c9h11no2, that occurs as a constituent of many proteins and is converted to tyrosine in the body. Ltyrosine, an essential amino acid that is often deficient in infants with pku. Material safety data sheet page 1 of 5 product name. Phenylalanine is an essential amino acid and the precursor of the amino acid tyrosine. Phenylalanine is an essential amino acid in humans and other mammals. Sigmaaldrich material safety data sheet product name d. The lform of phenylalanine is incorporated into proteins, while the dform acts as a painkiller.
Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. Pah encodes the enzyme phenylalanine hydroxylase that is the ratelimiting step in phenylalanine catabolism. Phenylalanine is an essential aromatic amino acid in humans provided by food, phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Lphenylalanine cas 63912 calbiochem msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. You can obtain all the essential amino acids by consuming a mixed diet containing the recommended intake of protein see chart 4 protein. The aromatic amino acid lphenylalanine is a vital constituent of proteins in all living organisms and serves as a versatile precursor for thousands of indispensable metabolites1. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. A nonfood source of phenylalanine is the artificial sweetener aspartame. Some medications used for depression stop the body from breaking down tyramine. Phenylalanine is a small organic chemical belonging to a group of substances called amino acids. D phenylalanine is the synthetic dextro isomer of phenylalanine, an essential amino acid with antidepressant and analgesic activities. Uses for dlphenylalanine mental acuity and emotional wellbeing. Material safety data sheet usp reference standards are sold for chemical test and assay purposes only, and not for human consumption. Sphenylalanine msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents.
Dphenylalanine, lphenylalanine, and the mix made in the laboratory called dlphenylalanine. First aid measures always seek professional medical attention after first aid measures are provided. Other information prepared by regulatory affairs thermo fisher scientific email. In humans, phenylalanine is an essential amino acid obtained through the diet primarily from plantbased sources, either directly or indirectly. Safety data sheet according to 29cfr19101200 and ghs rev. Material safety data sheet lphenylalanine 1 chemical product and company identification msds name. Amino acids are combined in nature to form proteins. Sigmaaldrich material safety data sheet date printed. L phenylalanine is an essential amino acid, which is biologically converted into ltyrosine, another one of the dnaencoded amino acids, which in turn is converted to ldopa and further converted into dopamine, norepinephrine, and epinephrine. You also can through below form to request documents for moa,ros,1hnmr. This compound, sold under the trade names equal and nutrasweet, is metabolized by the body into several chemical byproducts including phenylalanine.
Material safety data sheet dl phenylalanine msds section 1. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. N material safety data sheet section 1 boclphenylalanine 1 chemical product and company identification msds name. Evaluation of phenylalanine ammonia lyase between petroselinum crispum and rhodosporidium toruloides based on computational algorithms. Show this safety data sheet to the doctor in attendance. Phenylalanine was initially converted to phenylpyruvic acid by. Powered by create your own unique website with customizable templates. Product name 3,4dihydroxydlphenylalanine cas number 63843 ec number 2005660 chemical formula c. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Dphenylalanine is converted into tyrosine and tyrosine in turn is converted into ldopa, norepinephrine, and epinephrine, three key neurotransmitters. It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine. Uses for dl phenylalanine mental acuity and emotional wellbeing. Lcarnitine 20 mg100 g and taurine 40 mg100 g to help supply amounts normally found in human milk and foods of animal origin. Lphenylalanine is an essential amino acid, which is biologically converted into ltyrosine, another one of the dnaencoded amino acids, which in turn is converted to ldopa and further converted into dopamine, norepinephrine, and epinephrine.
Methods and material for containment and cleaning up methods for cleaning up wear protective clothing as described in section 8 of this safety data sheet. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using java or javascript. Phenylalanine definition of phenylalanine by the free. The information provided on this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Dphenylalanine is the synthetic dextro isomer of phenylalanine, an essential amino acid with antidepressant and analgesic activities. Lphenylalanine pa is an essential amino acid discussed in dr. Jan 05, 2020 a diet devoid of phenylalanine, tyrosine, and tryptophan may impair mood and increase irritability. Buy dlphenylalanine cas 150301, a biochemical for proteomics research, from santa cruz. This compound, sold under the trade names equal and nutrasweet, is metabolized by the body into. Phenylalanine is an amino acid, a building block of protein. Lphenylalanine msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. But the body naturally breaks down tyramine to get rid of it. Dl phenylalanine is a combination of the welltolerated essential amino acids, d phenylalanine and l phenylalanine.
Sds of lphenylalanyllphenylalanine, safety data sheets. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. Chemical product and company identification product name. Together, these compounds help promote mental functioning and support positive outlook. Dlphenylalanine cas 150301 scbt santa cruz biotechnology. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine. The information contained herein is applicable solely to the chemical substance when used as a usp reference standard and does not necessarily relate to any other use of the substance. We ask that users who download significant portions of the database cite the hmdb paper in any resulting. Refer to certificate of analysis for lot specific data including water content. Like tyrosine, phenylalanine is also a precursor for catecholamines including tyramine, dopamine, epinephrine, and norepinephrine.
D phenylalanine is converted into tyrosine and tyrosine in turn is converted into ldopa, norepinephrine, and epinephrine, three key neurotransmitters. Phenylalaninefree to allow greater intake of intact protein. The information in cameo chemicals comes from a variety of data sources. Lphenylalanine cas 63912 scbt santa cruz biotechnology. When we eat foods containing proteins, the proteins are broken down during digestion into their constituent amino acids. Physical and chemical properties molecular formula c9h11no2.
Rinse immediately with plenty of water, also under the eyelids, for at least. The primary use of d phenylalanine as a health supplement is the relief of discomfort. Lphenylalanine is an essential amino acid and is the only form of phenylalanine found in proteins. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. In one clinical trial with 155 depressed patients, a combination of l phenylalanine 250 mg daily and standard treatment was. Sds of 3bromolphenylalanine, safety data sheets, cas 82311. Together, these compounds promote mental functioning, support a positive outlook, and relax the musculoskeletal system. Enter synonyms, trade names or additional information found in section 1. Our bodies use some of these to make new proteins and other substances that.
Catecholamines are neurotransmitters that act as adrenalinlike substances. This usually prevents the tyramine from causing high blood pressure. Phenylalanine can increase a chemical in the body called tyramine. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Dlphenylalanine is a combination of the welltolerated essential amino acids, dphenylalanine and lphenylalanine. The recommended oral adult intake of lphenylalanine is 2. The primary use of dphenylalanine as a health supplement is the relief of discomfort.
Inhalation remove person to fresh air and keep comfortable for breathing. Phenylalanine is one of the socalled essential amino acids and must be obtained by the body from food. Pdf conversion of phenylalanine to benzaldehyde initiated. Large amounts of tyramine can cause high blood pressure.
Identification of a plastidial phenylalanine exporter that. L2amino3phenylpropionic acid company identification. Lalanyllalanyllphenylalanine 7amido4methylcoumarin cas. Ethanolsa south africa ethanol suppliermanufacturer, chemicals, bioreagents, biochemicals, specialty fine chemicals, perfumers alcohol.